The Eppendorf PiezoXpert provides piezo-assisted micromanipulation, enabling simple penetration in cells for microinjection or micromanipulation. Perforation of the cell membrane is supported by piezo impulses which are directly transferred to the capillary without any loss of intensity. Piezo-assisted micromanipulation improves the results of a variety of applications including transfer of embryonic or induced pluripotent stem cells into blastocysts and morulae, injection into mammalian oocytes and zygotes, and enucleation/nuclear transfer. The Eppendorf PiezoXpert forms the perfect system with Eppendorf micromanipulators, but it integrates just as easily with non-Eppendorf micromanipulation systems